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The antibody against CDC7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CDC7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03692A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDC7 |
| Target Synonyms | Hsk1; CDC7L1; HsCDC7; huCDC7; CDC7 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, SH-SY5Y, THP-1 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O00311 | Immunogen Sequence |
Uniprot Id
O00311
Target Species
Human
Target Name
CDC7
Target Full Name
Cell division cycle 7-related protein kinase
Target Function
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylate MCM2 and MCM3.
Target Subcellular Location
Nucleus.
Target Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, CDC7 subfamily
Target Synonyms
Cdc 7; CDC7; CDC7 cell division cycle 7; CDC7 cell division cycle 7 like 1; Cdc7 Kinase; CDC7 L1; Cdc7 like 1; CDC7 related kinase; CDC7-related kinase; CDC7_HUMAN; CDC7L 1; CDC7L1; Cell division cycle 7 homolog; Cell division cycle 7 kinase; Cell division cycle 7 like protein 1; Cell division cycle 7 related protein kinase; Cell division cycle 7-related protein kinase; HsCDC 7; HsCdc7; Hsk 1; Hsk1; HuCDC 7; huCdc7; MGC117361; MGC126237; MGC126238
Target Background
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
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