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The antibody against DRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11268A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DRD1 |
| Target Synonyms | DADR; DRD1A; DRD1 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | RKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT | Uniprot ID | P21728 |
Uniprot Id
P21728
Target Species
Human
Target Name
DRD1
Target Full Name
D(1A) dopamine receptor
Target Function
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Detected in caudate, nucleus accumbens and in the olfactory tubercle.
Target Research Area
Neuroscience
Target Synonyms
DRD1; D(1A dopamine receptor; Dopamine D1 receptor
Target Background
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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