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The antibody against SPT16 was raised in rabbit using the Recombinant Arabidopsis thaliana FACT complex subunit SPT16 protein (890-1074AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against SPT16 was raised in rabbit using the Recombinant Arabidopsis thaliana FACT complex subunit SPT16 protein (890-1074AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-44250A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPT16 |
| Target Synonyms | SPT16 antibody; At4g10710 antibody; T12H20.3 antibody; FACT complex subunit SPT16 antibody; Facilitates chromatin transcription complex subunit SPT16 antibody | Form | Liquid |
| Species Reactivity | Arabidopsis thaliana | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Arabidopsis thaliana FACT complex subunit SPT16 protein (890-1074AA) | Target Species | Arabidopsis thaliana (Mouse-ear cress) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O82491 |
Uniprot Id
O82491
Target Species
Arabidopsis thaliana
Target Name
SPT16
Target Function
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable).
Target Subcellular Location
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Target Protein Families
Peptidase M24 family, SPT16 subfamily
Target Tissue Specificity
Widely expressed. Present in embryos, shoots and roots, whereas it is not present in terminally differentiated cells such as mature trichoblasts or cells of the root cap (at protein level).
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