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The antibody against ruvA was raised in rabbit using the Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ruvA was raised in rabbit using the Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-20486A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ruvA |
| Target Synonyms | ruvA antibody; b1861 antibody; JW1850 antibody; Holliday junction ATP-dependent DNA helicase RuvA antibody; EC 3.6.4.12 antibody | Form | Liquid |
| Species Reactivity | Escherichia coli | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA) | Target Species | Escherichia coli (strain K12) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0A809 |
Uniprot Id
P0A809
Target Species
E.coli
Target Name
RUVA
Target Function
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.
Target Subcellular Location
Cytoplasm. Note=In 15% of cell localizes to discrete nucleoid foci (probable DNA damage sites) upon treatment with mitomycin C (MMC) for 2 hours.
Target Protein Families
RuvA family
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