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The antibody against ABCC10 was raised in rabbit using the Synthetic peptide of Human ABCC10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ABCC10 was raised in rabbit using the Synthetic peptide of Human ABCC10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-27883A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABCC10 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human ABCC10 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5T3U5 |
Uniprot Id
Q5T3U5
Target Species
Human
Target Name
ABCC10
Target Full Name
ATP-binding cassette sub-family C member 10
Target Function
ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel. Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCC family, Conjugate transporter (TC 3.A.1.208) subfamily
Target Tissue Specificity
[Isoform 1]: Specifically expressed in spleen.; [Isoform 2]: Widely expressed.
Target Synonyms
ABCC10; ATP binding cassette; sub family C (CFTR/MRP); member 10 ; ATP binding cassette; subfamily C; member 10 ; ATP-binding cassette sub-family C member 10; EST182763; mFLJ00002; MRP7 ; MRP7_HUMAN; Multidrug resistance associated protein 7; Multidrug resistance-associated protein 7; SIMRP7
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