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The antibody against ABCC10 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against ABCC10 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human MRP7. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of COS7 cells using MRP7 Polyclonal Antibody
Western Blot analysis of Jurkat A549 cells using MRP7 Polyclonal Antibody2
| Cat.No | ADC-38209A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABCC10 |
| Form | Liquid | Species Reactivity | Human, Monkey |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human MRP7. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5T3U5 |
Uniprot Id
Q5T3U5
Target Species
Human
Target Name
ABCC10
Target Full Name
ATP-binding cassette sub-family C member 10
Target Function
ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel. Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
ABC transporter superfamily, ABCC family, Conjugate transporter (TC 3.A.1.208) subfamily
Target Tissue Specificity
[Isoform 1]: Specifically expressed in spleen.; [Isoform 2]: Widely expressed.
Target Synonyms
ABCC10; ATP binding cassette; sub family C (CFTR/MRP); member 10 ; ATP binding cassette; subfamily C; member 10 ; ATP-binding cassette sub-family C member 10; EST182763; mFLJ00002; MRP7 ; MRP7_HUMAN; Multidrug resistance associated protein 7; Multidrug resistance-associated protein 7; SIMRP7
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