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The antibody against ACAP1 was raised in rabbit using the Recombinant Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 protein (1-266AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ACAP1 was raised in rabbit using the Recombinant Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 protein (1-266AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human lung tissue using ACAP1 Antibody at dilution of 1:1002
| Cat.No | ADC-20211A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ACAP1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 protein (1-266AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15027 |
Uniprot Id
Q15027
Target Species
Human
Target Name
ACAP1
Target Full Name
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Target Function
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Target Subcellular Location
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Tissue Specificity
Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
Target Synonyms
ACAP 1; ACAP1; ACAP1_HUMAN; Arf GAP with coiled coil ANK repeat and PH domains 1; Arf GAP with coiled coil; ankyrin repeat; and pleckstrin homology domains 1; Arf-GAP with coiled-coil; ANK repeat and PH domain-containing protein 1; ArfGAP with coiled-coil; ankyrin repeat and PH domains 1; CENT B1; Centaurin beta 1; Centaurin-beta-1; CENTB 1; Cnt b1; Cnt-b1; Cntb1; KIAA0050
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