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The antibody against ADCY1 was raised in rabbit using the Recombinant Human Adenylate cyclase type 1 protein (416-610AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ADCY1 was raised in rabbit using the Recombinant Human Adenylate cyclase type 1 protein (416-610AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human lung cancer using ADCY1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using ADCY1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-15473A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADCY1 |
| Target Synonyms | Adenylate cyclase 1; fetal brain; type I antibody; 3' | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Adenylate cyclase type 1 protein (416-610AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q08828 |
Uniprot Id
Q08828
Target Species
Human
Target Name
ADCY1
Target Full Name
Adenylate cyclase type 1
Target Function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.
Target Involvement
Deafness, autosomal recessive, 44 (DFNB44)
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft.
Target Protein Families
Adenylyl cyclase class-4/guanylyl cyclase family
Target Tissue Specificity
Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Brain, retina and adrenal medulla.
Target Synonyms
Adenylate cyclase 1; fetal brain; type I; 3',5'-cyclic AMP synthetase; AC1; Adcy1; ADCY1_HUMAN; adenyl cyclase; Adenylate cyclase 1; adenylate cyclase 1 (brain); Adenylate cyclase type 1; Adenylate cyclase type I; Adenylyl cyclase 1; ATP pyrophosphate lyase; ATP pyrophosphate-lyase 1; Brain adenylate cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase; deafness; autosomal recessive 44; DFNB44
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