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Rabbit anti-Human ADNP Polyclonal Antibody

The antibody against ADNP was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human ADNP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-35803A

The antibody against ADNP was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human ADNP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-35803A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADNP
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the N-terminal region of Human ADNP.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H2P0
Background Information
  • Uniprot Id

    Q9H2P0

  • Target Species

    Human

  • Target Name

    ADNP

  • Target Full Name

    Activity-dependent neuroprotector homeobox protein

  • Target Function

    Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.

  • Target Involvement

    Helsmoortel-van der Aa syndrome (HVDAS)

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissue

  • Target Synonyms

    Activity dependent neuroprotective protein; Activity dependent neuroprotector ; Activity-dependent neuroprotective protein; Activity-dependent neuroprotector homeobox protein; Adnp; ADNP_HUMAN; KIAA0784

  • Target Background

    Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

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