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The antibody against AEBP1 was raised in rabbit using the Recombinant Human Adipocyte enhancer-binding protein 1 protein (46-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against AEBP1 was raised in rabbit using the Recombinant Human Adipocyte enhancer-binding protein 1 protein (46-234AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-04775A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AEBP1 |
| Target Synonyms | AEBP1 antibody; ACLP antibody; Adipocyte enhancer-binding protein 1 antibody; AE-binding protein 1 antibody; Aortic carboxypeptidase-like protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Adipocyte enhancer-binding protein 1 protein (46-234AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IUX7 |
Uniprot Id
Q8IUX7
Target Species
Human
Target Name
AEBP1
Target Full Name
Adipocyte enhancer-binding protein 1
Target Function
As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix.; May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.
Target Subcellular Location
[Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm. Nucleus.
Target Protein Families
Peptidase M14 family
Target Tissue Specificity
Expressed in osteoblast and visceral fat.
Target Synonyms
AEBP1; ACLP; Adipocyte enhancer-binding protein 1; AE-binding protein 1; Aortic carboxypeptidase-like protein
Target Background
This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma.
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