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The antibody against AGBL3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CCP3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against AGBL3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CCP3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-35333A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGBL3 |
| Target Synonyms | CCP3 antibody; Agbl3 antibody; ATP/GTP-binding protein-like 3 antibody; CBPC3_HUMAN antibody; Cytosolic carboxypeptidase 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human CCP3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NEM8 |
Uniprot Id
Q8NEM8
Target Species
Human
Target Name
AGBL3
Target Full Name
Cytosolic carboxypeptidase 3
Target Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins.; Metallocarboxypeptidase that mediates tubulin deglutamylation.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
Peptidase M14 family
Target Synonyms
CCP3; Agbl3; ATP/GTP-binding protein-like 3; CBPC3_HUMAN; Cytosolic carboxypeptidase 3
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