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The antibody against AHRR was raised in rabbit using the Synthetic peptide of Human AHRR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against AHRR was raised in rabbit using the Synthetic peptide of Human AHRR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-27096A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AHRR |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human AHRR | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A9YTQ3 |
Uniprot Id
A9YTQ3
Target Species
Human
Target Name
AHRR
Target Full Name
Aryl hydrocarbon receptor repressor
Target Function
Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment.
Target Tissue Specificity
Highly expressed in testis, lung, ovary, spleen and pancreas. Highly expressed in mononuclear cells (MNCs) from umbilical cord blood. Isoform 3 is highly expressed in lung, kidney, spleen and thymus. Down-regulated malignant tissue from different anatomic
Target Synonyms
AHH; AhR repressor; AhRR; AHRR_HUMAN; aryl hydrocarbon hydroxylase regulator; aryl hydrocarbon receptor regulator; Aryl hydrocarbon receptor repressor; Arylhydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; Dioxin receptor repressor; KIAA1234; MGC167813; MGC176630; OTTHUMP00000221488; OTTHUMP00000221489
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