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Rabbit anti-Human AMPD3 Polyclonal Antibody

The antibody against AMPD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03071A

The antibody against AMPD3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03071A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAMPD3
Target SynonymsAMPD3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesNIH/3T3, RAW264.7ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1).Target SpeciesHuman
Uniprot IDQ01432Immunogen Sequence
Background Information
  • Uniprot Id

    Q01432

  • Target Species

    Human

  • Target Name

    AMPD3

  • Target Full Name

    AMP deaminase 3

  • Target Function

    AMP deaminase plays a critical role in energy metabolism.

  • Target Involvement

    Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)

  • Target Protein Families

    Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family

  • Target Synonyms

    AMPD3

  • Target Background

    This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

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