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The antibody against AP1M2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 164-423 of human AP1M2 (NP_005489.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against AP1M2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 164-423 of human AP1M2 (NP_005489.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01511A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AP1M2 |
| Target Synonyms | mu2; MU1B; MU-1B; HSMU1B; AP1-mu2; AP1M2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 22Rv1, BT-474, HepG2, Mouse lung, Mouse small intestine | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 164-423 of human AP1M2 (NP_005489.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y6Q5 | Immunogen Sequence |
Uniprot Id
Q9Y6Q5
Target Species
Human
Target Name
AP1M2
Target Full Name
AP-1 complex subunit mu-2
Target Function
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Target Subcellular Location
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Target Protein Families
Adaptor complexes medium subunit family
Target Synonyms
mu2; MU1B; MU-1B; HSMU1B; AP1-mu2; AP1M2
Target Background
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alternative splicing results in multiple transcript variants.
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