Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against APIP was raised in rabbit using the Fusion protein of Human APIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against APIP was raised in rabbit using the Fusion protein of Human APIP as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-32427A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APIP |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human APIP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96GX9 |
Uniprot Id
Q96GX9
Target Species
Human
Target Name
APIP
Target Full Name
Methylthioribulose-1-phosphate dehydratase
Target Function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Aldolase class II family, MtnB subfamily
Target Tissue Specificity
Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
Target Research Area
Cell Biology
Target Synonyms
Apaf1 Interacting Protein; APAF1-interacting protein; APIP; APIP2; CG129; CGI 29; CGI29; dJ179L10.2; MMRP19; Monocyte/macrophage protein 19; MTNB_HUMAN; MTRu 1 P dehydratase; MTRu-1-P dehydratase; Probable methylthioribulose 1 phosphate dehydratase; Probable methylthioribulose-1-phosphate dehydratase
Target Background
Enables identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in several processes, including L-methionine salvage from methylthioadenosine; protein homotetramerization; and pyroptosis. Located in cytoplasm.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
