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The antibody against APOL3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ApoL3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against APOL3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ApoL3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-33693A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APOL3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human ApoL3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95236 |
Uniprot Id
O95236
Target Species
Human
Target Name
APOL3
Target Full Name
Apolipoprotein L3
Target Function
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Apolipoprotein L family
Target Tissue Specificity
Widely expressed; the highest levels are in prostate, lung and placenta; also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland; levels are low in brain, heart, fetal liver, pancreas and
Target Synonyms
ApoL III; ApoL-III; APOL3; APOL3_HUMAN; APOLIII; Apolipoprotein L 3; Apolipoprotein L III; Apolipoprotein L-III; Apolipoprotein L3; Apolipoprotein LIII; CG12 1; CG12_1; CG121; TNF inducible protein CG12 1; TNF-inducible protein CG12-1
Target Background
This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants.
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