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The antibody against ARHGAP18 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ARHGAP18 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-07523A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARHGAP18 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N392 |
Uniprot Id
Q8N392
Target Species
Human
Target Name
ARHGAP18
Target Full Name
Rho GTPase-activating protein 18
Target Function
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
Target Subcellular Location
Cytoplasm.
Target Synonyms
4833419J07Rik; AI314906; AI843501; Arhgap18; bA307O14.2; FLJ25728; MacGAP; MGC126757; MGC138145; OTTHUMP00000017190; OTTMUSP00000028606; RHG18_HUMAN; Rho GTPase-activating protein 18; Rho-type GTPase-activating protein 18; SENEX
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