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The antibody against ARSA was raised in rabbit using the Synthesized peptide derived from internal of Human ARSA. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against ARSA was raised in rabbit using the Synthesized peptide derived from internal of Human ARSA. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from Jurkat cells and COLO cells, using ARSA antibody.
Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using ARSA antibody.2
| Cat.No | ADC-41468A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARSA |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ARSA. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P15289 |
Uniprot Id
P15289
Target Species
Human
Target Name
ARSA
Target Full Name
Arylsulfatase A
Target Function
Hydrolyzes cerebroside sulfate.
Target Involvement
Metachromatic leukodystrophy (MLD); Multiple sulfatase deficiency (MSD)
Target Subcellular Location
Endoplasmic reticulum. Lysosome.
Target Protein Families
Sulfatase family
Target Synonyms
arsA; ARSA_HUMAN; arylsulfatase A; Arylsulfatase A component C; As 2; AS A; As2; ASA; AW212749; C230037L18Rik; Cerebroside-sulfatase; metachromatic leucodystrophy; MGC125207; MLD; OTTHUMP00000196546; OTTHUMP00000196548; TISP73
Target Background
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
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