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The antibody against ARSE was raised in rabbit using the Recombinant Human Arylsulfatase E protein (352-494AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ARSE was raised in rabbit using the Recombinant Human Arylsulfatase E protein (352-494AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-06159A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARSE |
| Target Synonyms | ARSL antibody; ARSE antibody; Arylsulfatase L antibody; EC 3.1.6.- antibody; Arylsulfatase E antibody; ASE antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Arylsulfatase E protein (352-494AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51690 |
Uniprot Id
P51690
Target Species
Human
Target Name
ARSL
Target Full Name
Arylsulfatase L
Target Function
Exhibits arylsulfatase activity towards the artifical substrate 4-methylumbelliferyl sulfate. May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates.
Target Involvement
Chondrodysplasia punctata 1, X-linked recessive (CDPX1)
Target Subcellular Location
Golgi apparatus, Golgi stack.
Target Protein Families
Sulfatase family
Target Tissue Specificity
Expressed in the pancreas, liver and kidney.
Target Synonyms
ARSL; ARSE; Arylsulfatase L; EC 3.1.6.-; Arylsulfatase E; ASE
Target Background
Arylsulfatase E is a member of the sulfatase family. It is glycosylated postranslationally and localized to the golgi apparatus. Sulfatases are essential for the correct composition of bone and cartilage matrix. X-linked chondrodysplasia punctata, a disease characterized by abnormalities in cartilage and bone development, has been linked to mutations in this gene. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the Y chromosome.
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