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The antibody against ASB7 was raised in rabbit using the Recombinant Human Ankyrin repeat and SOCS box protein 7 protein (1-274AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ASB7 was raised in rabbit using the Recombinant Human Ankyrin repeat and SOCS box protein 7 protein (1-274AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-18395A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASB7 |
| Target Synonyms | ASB7Ankyrin repeat and SOCS box protein 7 antibody; ASB-7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ankyrin repeat and SOCS box protein 7 protein (1-274AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H672 |
Uniprot Id
Q9H672
Target Species
Human
Target Name
ASB7
Target Full Name
Ankyrin repeat and SOCS box protein 7
Target Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Target Protein Families
Ankyrin SOCS box (ASB) family
Target Synonyms
ASB7Ankyrin repeat and SOCS box protein 7; ASB-7
Target Background
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
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