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The antibody against ATE1 was raised in rabbit using the Recombinant Human Arginyl-tRNA--protein transferase 1 protein (105-253AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ATE1 was raised in rabbit using the Recombinant Human Arginyl-tRNA–protein transferase 1 protein (105-253AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-08065A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATE1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Arginyl-tRNA--protein transferase 1 protein (105-253AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95260 |
Uniprot Id
O95260
Target Species
Human
Target Name
ATE1
Target Full Name
Arginyl-tRNA--protein transferase 1
Target Function
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.
Target Subcellular Location
[Isoform ATE1-1]: Nucleus. Cytoplasm.; [Isoform ATE1-2]: Cytoplasm.
Target Protein Families
R-transferase family
Target Synonyms
AI225793; Arginine tRNA protein transferase 1; Arginine-tRNA--protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; Ate1; ATE1_HUMAN; AW547406; EC 2.3.2.8; MGC26724; OTTHUMP00000020637; OTTHUMP00000058665; R transferase 1; R-transferase 1
Target Background
This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants.
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