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The antibody against ATXN7 was raised in rabbit using the Recombinant Human Ataxin-7 protein (402-503AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ATXN7 was raised in rabbit using the Recombinant Human Ataxin-7 protein (402-503AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-08063A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATXN7 |
| Target Synonyms | ATXN7 antibody; SCA7Ataxin-7 antibody; Spinocerebellar ataxia type 7 protein antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ataxin-7 protein (402-503AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15265 |
Uniprot Id
O15265
Target Species
Human
Target Name
ATXN7
Target Full Name
Ataxin-7
Target Function
Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization.
Target Involvement
Spinocerebellar ataxia 7 (SCA7)
Target Subcellular Location
[Isoform a]: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.; [Isoform b]: Cytoplasm.
Target Protein Families
Ataxin-7 family
Target Tissue Specificity
Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymp
Target Research Area
Neuroscience
Target Synonyms
ATXN7; SCA7Ataxin-7; Spinocerebellar ataxia type 7 protein
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