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The antibody against B4GALNT1 was raised in rabbit using the Synthesized peptide derived from internal of Human B4GALNT1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against B4GALNT1 was raised in rabbit using the Synthesized peptide derived from internal of Human B4GALNT1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HeLa cells, K562 cells, HepG2 cells and HuvEC cells, using B4GALNT1 antibody.
| Cat.No | ADC-41418A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | B4GALNT1 |
| Target Synonyms | 4-N-ACETYLGALACTOSAMINYLTRANSFERASE 1 antibody; BETA-1 | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human B4GALNT1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q00973 |
Uniprot Id
Q00973
Target Species
Human
Target Name
B4GALNT1
Target Full Name
Beta-1,4 N-acetylgalactosaminyltransferase 1
Target Function
Involved in the biosynthesis of gangliosides GM2, GD2, GT2 and GA2 from GM3, GD3, GT3 and GA3, respectively.
Target Involvement
Spastic paraplegia 26, autosomal recessive (SPG26)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 2 family
Target Synonyms
GALGT; SPG26; GALNACT; GalNAc-T; B4GALNT1
Target Background
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1, 4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.
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