Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against BANP was raised in rabbit using the Recombinant Human Protein BANP protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against BANP was raised in rabbit using the Recombinant Human Protein BANP protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using BANP Antibody at dilution of 1:1002
| Cat.No | ADC-44225A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BANP |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein BANP protein (1-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N9N5 |
Uniprot Id
Q8N9N5
Target Species
Human
Target Name
BANP
Target Full Name
Protein BANP
Target Function
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest.
Target Subcellular Location
Nucleus.
Target Protein Families
BANP/SMAR1 family
Target Tissue Specificity
Down-regulated in breast cancer cell lines.
Target Synonyms
AAH09424; Banp; BANP_HUMAN; BEN domain-containing protein 1; BEND1; BTG3 associated nuclear protein isoform a; Btg3-associated nuclear protein; DKFZp761H172; FLJ 10177; FLJ 20538; FLJ10177; FLJ20538; Protein BANP; Scaffold/Matrix associated region 1; Scaffold/matrix-associated region-1-binding protein; SMAR 1; SMAR1; SMARBP 1; SMARBP1
Target Background
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
