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Rabbit anti-Human BATF3 Polyclonal Antibody

The antibody against BATF3 was raised in rabbit using the Recombinant Human Basic leucine zipper transcriptional factor ATF-like 3 protein (2-65AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-13231A

The antibody against BATF3 was raised in rabbit using the Recombinant Human Basic leucine zipper transcriptional factor ATF-like 3 protein (2-65AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-13231A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBATF3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Basic leucine zipper transcriptional factor ATF-like 3 protein (2-65AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NR55
Background Information
  • Uniprot Id

    Q9NR55

  • Target Species

    Human

  • Target Name

    BATF3

  • Target Full Name

    Basic leucine zipper transcriptional factor ATF-like 3

  • Target Function

    AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family

  • Target Synonyms

    BATF3; SNFTBasic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT

  • Target Background

    This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.

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