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The antibody against BAZ2B was raised in rabbit using the Recombinant Human Bromodomain adjacent to zinc finger domain protein 2B protein (139-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against BAZ2B was raised in rabbit using the Recombinant Human Bromodomain adjacent to zinc finger domain protein 2B protein (139-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06271A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BAZ2B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bromodomain adjacent to zinc finger domain protein 2B protein (139-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UIF8 |
Uniprot Id
Q9UIF8
Target Species
Human
Target Name
BAZ2B
Target Full Name
Bromodomain adjacent to zinc finger domain protein 2B
Target Function
Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI. Involved in positively modulating the rate of age-related behavioral deterioration. Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with histone methyltransferase EHMT1.
Target Subcellular Location
Nucleus.
Target Protein Families
WAL family
Target Tissue Specificity
Expressed at varying levels in several tissues, whereas a smaller transcript was expressed specifically in testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
BAZ2B; BAZ2B_HUMAN; Bromodomain adjacent to zinc finger domain 2B; Bromodomain adjacent to zinc finger domain protein 2B; DKFZp434H071; DKFZp762I0516; FLJ45644; hWALp4; OTTHUMP00000162897; OTTHUMP00000162898; WALp4
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