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The antibody against BIN2 was raised in rabbit using the Recombinant Human Bridging integrator 2 protein (290-496AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against BIN2 was raised in rabbit using the Recombinant Human Bridging integrator 2 protein (290-496AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06955A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BIN2 |
| Target Synonyms | BIN2 antibody; BRAP1Bridging integrator 2 antibody; Breast cancer-associated protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bridging integrator 2 protein (290-496AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBW5 |
Uniprot Id
Q9UBW5
Target Species
Human
Target Name
BIN2
Target Full Name
Bridging integrator 2
Target Function
Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.
Target Subcellular Location
Cytoplasm. Cell projection, podosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup.
Target Tissue Specificity
Detected in natural killer cells (at protein level). Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.
Target Synonyms
BIN2; BRAP1Bridging integrator 2; Breast cancer-associated protein 1
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