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The antibody against BTBD1 was raised in rabbit using the Human BTBD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against BTBD1 was raised in rabbit using the Human BTBD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-49116A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BTBD1 |
| Target Synonyms | BTBD1 antibody; C15orf1 antibody; NS5ATP8BTB/POZ domain-containing protein 1 antibody; Hepatitis C virus NS5A-transactivated protein 8 antibody; HCV NS5A-transactivated protein 8 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human BTBD1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0C5 |
Uniprot Id
Q9H0C5
Target Species
Human
Target Name
BTBD1
Target Full Name
BTB/POZ domain-containing protein 1
Target Function
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Ubiquitous; highest levels in testes, heart and skeletal muscle.
Target Synonyms
BTBD1; C15orf1; NS5ATP8BTB/POZ domain-containing protein 1; Hepatitis C virus NS5A-transactivated protein 8; HCV NS5A-transactivated protein 8
Target Background
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
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