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Rabbit anti-Human C1D Polyclonal Antibody

The antibody against C1D was raised in rabbit using the Human C1D as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-49100A

The antibody against C1D was raised in rabbit using the Human C1D as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$600.00

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Specifications


Cat.No ADC-49100A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC1D
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman C1DTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ13901
Background Information
  • Uniprot Id

    Q13901

  • Target Species

    Human

  • Target Name

    C1D

  • Target Full Name

    Nuclear nucleic acid-binding protein C1D

  • Target Function

    Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Nucleus, nucleolus.

  • Target Protein Families

    C1D family

  • Target Tissue Specificity

    Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung an

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    1110036E10Rik; AI875855; C1D; C1D DNA binding protein; C1D_HUMAN; hC1D; LRP1; MGC12261; MGC14659; MGC188504; Nuclear DNA binding protein; Nuclear nucleic acid binding protein C1D; Nuclear nucleic acid-binding protein C1D; rCG23324; RGD1560600; Small unique nuclear receptor corepressor; SUNCOR

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