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The antibody against CA14 was raised in rabbit using the Recombinant Human Carbonic anhydrase 14 protein (16-290AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CA14 was raised in rabbit using the Recombinant Human Carbonic anhydrase 14 protein (16-290AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using CA14 Antibody at dilution of 1:1002
| Cat.No | ADC-43858A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CA14 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Carbonic anhydrase 14 protein (16-290AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9ULX7 |
Uniprot Id
Q9ULX7
Target Species
Human
Target Name
CA14
Target Full Name
Carbonic anhydrase 14
Target Function
Reversible hydration of carbon dioxide.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Alpha-carbonic anhydrase family
Target Tissue Specificity
High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
Target Synonyms
CA 14; CA XIV; CA-XIV; CA14; CAH14_HUMAN; Carbonate dehydratase XIV; Carbonic anhydrase 14; Carbonic anhydrase XIV; Carbonic dehydratase; CAXIV; UNQ690/PRO1335
Target Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
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