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Rabbit anti-Human CALCR Polyclonal Antibody

The antibody against CALCR was raised in rabbit using the Fusion protein of Human CALCR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-32298A

The antibody against CALCR was raised in rabbit using the Fusion protein of Human CALCR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-32298A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCALCR
Target SynonymsCALCR; Calcitonin receptor; CT-RFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human CALCRTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP30988
Background Information
  • Uniprot Id

    P30988

  • Target Species

    Human

  • Target Name

    CALCR

  • Target Full Name

    Calcitonin receptor

  • Target Function

    This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.; Receptor for calcitonin but is unable to couple to G proteins and activate adenylyl cyclase. Does not undergo receptor internalization following ligand binding.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 2 family

  • Target Synonyms

    CALCR; Calcitonin receptor; CT-R

  • Target Background

    This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.

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