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Rabbit anti-Human CALML5 Polyclonal Antibody

The antibody against CALML5 was raised in rabbit using the Human CALML5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-53924A

The antibody against CALML5 was raised in rabbit using the Human CALML5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-53924A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCALML5
Target SynonymsCALL5_HUMAN antibody; CALML5 antibody; Calmodulin like 5 antibody; Calmodulin-like protein 5 antibody; Calmodulin-like skin protein antibody; CLSP antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CALML5Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NZT1
Background Information
  • Uniprot Id

    Q9NZT1

  • Target Species

    Human

  • Target Name

    CALML5

  • Target Full Name

    Calmodulin-like protein 5

  • Target Function

    Binds calcium. May be involved in terminal differentiation of keratinocytes.

  • Target Tissue Specificity

    Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    CALL5_HUMAN; CALML5; Calmodulin like 5; Calmodulin-like protein 5; Calmodulin-like skin protein; CLSP

  • Target Background

    This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

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