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The antibody against CCNY was raised in rabbit using the Human CCNY as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against CCNY was raised in rabbit using the Human CCNY as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-49018A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCNY |
| Target Synonyms | CCNY antibody; C10orf9 antibody; CBCP1 antibody; CFP1Cyclin-Y antibody; Cyc-Y antibody; Cyclin box protein 1 antibody; Cyclin fold protein 1 antibody; cyclin-X antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human CCNY | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8ND76 |
Uniprot Id
Q8ND76
Target Species
Human
Target Name
CCNY
Target Full Name
Cyclin-Y
Target Function
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Target Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.; [Isoform 3]: Nucleus.
Target Protein Families
Cyclin family, Cyclin Y subfamily
Target Tissue Specificity
Widely expressed.
Target Synonyms
CCNY; C10orf9; CBCP1; CFP1Cyclin-Y; Cyc-Y; Cyclin box protein 1; Cyclin fold protein 1; cyclin-X
Target Background
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).
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