Rabbit anti-Human CDC42EP3 Polyclonal Antibody

The antibody against CDC42EP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01285A

Number

Cat.No	ADA-01285A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CDC42EP3
Target Synonyms	UB1; CEP3; BORG2; CDC42EP3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	NIH/3T3, Rat heart, 293T, K-562	Application	ELISA, WB

Cat.No

ADA-01285A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CDC42EP3

Target Synonyms

UB1; CEP3; BORG2; CDC42EP3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

NIH/3T3, Rat heart, 293T, K-562

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2).	Target Species	Human
Uniprot ID	Q9UKI2	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2).

Target Species

Human

Uniprot ID

Q9UKI2

Immunogen Sequence

Background Information

Uniprot Id

Q9UKI2
Target Species

Human
Target Name

CDC42EP3
Target Full Name

Cdc42 effector protein 3
Target Function

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Target Subcellular Location

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families

BORG/CEP family
Target Tissue Specificity

Highly expressed in the heart and weakly in the brain.
Target Synonyms

CDC42EP3; BORG2; CEP3Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein
Target Background

This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human CDC42EP3 Polyclonal Antibody

Specifications

Immunogen Information

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