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The antibody against CDC42EP3 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human CDC42EP3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CDC42EP3 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human CDC42EP3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from K562 cells, using CDC42EP3 antibody.
| Cat.No | ADC-41354A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDC42EP3 |
| Target Synonyms | CDC42EP3 antibody; BORG2 antibody; CEP3Cdc42 effector protein 3 antibody; Binder of Rho GTPases 2 antibody; MSE55-related Cdc42-binding protein antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human CDC42EP3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UKI2 |
Uniprot Id
Q9UKI2
Target Species
Human
Target Name
CDC42EP3
Target Full Name
Cdc42 effector protein 3
Target Function
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Target Subcellular Location
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Target Protein Families
BORG/CEP family
Target Tissue Specificity
Highly expressed in the heart and weakly in the brain.
Target Synonyms
CDC42EP3; BORG2; CEP3Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein
Target Background
This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
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