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The antibody against CHMP7 was raised in rabbit using the Recombinant Human Charged multivesicular body protein 7 protein (1-290AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CHMP7 was raised in rabbit using the Recombinant Human Charged multivesicular body protein 7 protein (1-290AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate cancer using CHMP7 Antibody at dilution of 1:100
| Cat.No | ADC-22754A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHMP7 |
| Target Synonyms | CHMP7Charged multivesicular body protein 7 antibody; Chromatin-modifying protein 7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Charged multivesicular body protein 7 protein (1-290AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WUX9 |
Uniprot Id
Q8WUX9
Target Species
Human
Target Name
CHMP7
Target Full Name
Charged multivesicular body protein 7
Target Function
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway.
Target Subcellular Location
Cytoplasm. Nucleus envelope.
Target Protein Families
SNF7 family
Target Research Area
Signal Transduction
Target Synonyms
CHMP7Charged multivesicular body protein 7; Chromatin-modifying protein 7
Target Background
Involved in several processes, including late endosome to vacuole transport; midbody abscission; and mitotic nuclear division. Located in cytosol; nuclear envelope; and nucleoplasm. Part of ESCRT III complex. Colocalizes with chromatin.
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