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Rabbit anti-Human CHRM4 Polyclonal Antibody

The antibody against CHRM4 was raised in rabbit using the Synthetic peptide of Human CHRM4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-28685A

The antibody against CHRM4 was raised in rabbit using the Synthetic peptide of Human CHRM4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-28685A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCHRM4
Target SynonymsCHRM4; Muscarinic acetylcholine receptor M4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human CHRM4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP08173
Background Information
  • Uniprot Id

    P08173

  • Target Species

    Human

  • Target Name

    CHRM4

  • Target Full Name

    Muscarinic acetylcholine receptor M4

  • Target Function

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM4 sub-subfamily

  • Target Synonyms

    CHRM4; Muscarinic acetylcholine receptor M4

  • Target Background

    The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition.

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