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The antibody against COA1 was raised in rabbit using the Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against COA1 was raised in rabbit using the Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human kidney tissue using COA1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using COA1 Antibody at dilution of 1:1002
Immunofluorescent analysis of U251 cells using COA1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-22198A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COA1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cytochrome c oxidase assembly factor 1 homolog protein (38-146AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZY4 |
Uniprot Id
Q9GZY4
Target Species
Human
Target Name
COA1
Target Full Name
Cytochrome c oxidase assembly factor 1 homolog
Target Function
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Target Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Target Protein Families
COA1 family
Target Research Area
Cancer
Target Synonyms
COA1; C7orf44; MITRAC15Cytochrome c oxidase assembly factor 1 homolog; Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa
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