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The antibody against COL8A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(VIII) chain protein (572-744AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against COL8A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(VIII) chain protein (572-744AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-22160A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL8A1 |
| Target Synonyms | C3orf7 antibody; CO8A1_HUMAN antibody; COL8A1 antibody; Collagen alpha 1(VIII) chain [Precursor] antibody; Endothelial collagen antibody; MGC9568 antibody; Vastatin antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Collagen alpha-1(VIII) chain protein (572-744AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P27658 |
Uniprot Id
P27658
Target Species
Human
Target Name
COL8A1
Target Full Name
Collagen alpha-1(VIII) chain
Target Function
Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.; Vastatin, the C-terminal fragment comprising the NC1 domain, inhibits aortic endothelial cell proliferation and causes cell apoptosis.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Target Tissue Specificity
Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve b
Target Research Area
Cardiovascular
Target Synonyms
C3orf7; CO8A1_HUMAN; COL8A1; Collagen alpha 1(VIII) chain [Precursor]; Endothelial collagen; MGC9568; Vastatin
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