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The antibody against COL9A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL9A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against COL9A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL9A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of HepG2 cells using COL9A1 Polyclonal Antibody
| Cat.No | ADC-36371A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL9A1 |
| Target Synonyms | COL9A1Collagen alpha-1(IX) chain antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human COL9A1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20849 |
Uniprot Id
P20849
Target Species
Human
Target Name
COL9A1
Target Full Name
Collagen alpha-1(IX) chain
Target Function
Structural component of hyaline cartilage and vitreous of the eye.
Target Involvement
Multiple epiphyseal dysplasia 6 (EDM6); Stickler syndrome 4 (STL4)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Target Synonyms
COL9A1Collagen alpha-1(IX) chain
Target Background
This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
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