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The antibody against DARS2 was raised in rabbit using the Human DARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against DARS2 was raised in rabbit using the Human DARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-53625A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DARS2 |
| Target Synonyms | DARS2 antibody; Aspartate--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.12 antibody; Aspartyl-tRNA synthetase antibody; AspRS antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human DARS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PI48 |
Uniprot Id
Q6PI48
Target Species
Human
Target Name
DARS2
Target Full Name
Aspartate--tRNA ligase, mitochondrial
Target Involvement
Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family, Type 1 subfamily
Target Synonyms
DARS2; Aspartate--tRNA ligase; mitochondrial; EC 6.1.1.12; Aspartyl-tRNA synthetase; AspRS
Target Background
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
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