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The antibody against DDX31 was raised in rabbit using the Recombinant Human Probable ATP-dependent RNA helicase DDX31 protein (560-851AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DDX31 was raised in rabbit using the Recombinant Human Probable ATP-dependent RNA helicase DDX31 protein (560-851AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using DDX31 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using DDX31 Antibody at dilution of 1:1002
| Cat.No | ADC-22746A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DDX31 |
| Target Synonyms | DDX31Probable ATP-dependent RNA helicase DDX31 antibody; EC 3.6.4.13 antibody; DEAD box protein 31 antibody; Helicain antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Probable ATP-dependent RNA helicase DDX31 protein (560-851AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H8H2 |
Uniprot Id
Q9H8H2
Target Species
Human
Target Name
DDX31
Target Full Name
ATP-dependent DNA helicase DDX31
Target Function
Probable ATP-dependent RNA helicase. Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
DEAD box helicase family, DDX31/DBP7 subfamily
Target Tissue Specificity
Weakly or undetectably expressed in normal organs. Up-regulated in renal cell carcinoma.
Target Synonyms
DDX31Probable ATP-dependent RNA helicase DDX31; EC 3.6.4.13; DEAD box protein 31; Helicain
Target Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.
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