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The antibody against DECR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DECR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11152A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DECR1 |
| Target Synonyms | DECR; NADPH; SDR18C1; DECR1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse liver, SK-BR-3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q16698 | Immunogen Sequence |
Uniprot Id
Q16698
Target Species
Human
Target Name
DECR1
Target Full Name
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
Target Function
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Target Involvement
2,4-dienoyl-CoA reductase deficiency (DECRD)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily
Target Tissue Specificity
Heart = liver = pancreas > kidney >> skeletal muscle = lung.
Target Synonyms
1200012F07Rik; 2; 2,4 dienoyl CoA reductase [NADPH]; 2,4 dienoyl CoA reductase 1; 2,4 dienoyl CoA reductase mitochondrial; 2,4-dienoyl-CoA reductase; mitochondrial; 4 enoyl CoA reductase; 4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; DECR 1; DECR; DECR_HUMAN; DECR1; Nadph; OTTMUSP00000004962; RP23-338J24.3; SDR18C1; Short chain dehydrogenase/reductase family 18C member 1
Target Background
Enables 2, 4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in cytosol; mitochondrion; and nucleoplasm. Part of catalytic complex.
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