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The antibody against DIXDC1 was raised in rabbit using the Recombinant Human Dixin protein (70-333AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against DIXDC1 was raised in rabbit using the Recombinant Human Dixin protein (70-333AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-02292A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DIXDC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dixin protein (70-333AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q155Q3 |
Uniprot Id
Q155Q3
Target Species
Human
Target Name
DIXDC1
Target Full Name
Dixin
Target Function
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Target Subcellular Location
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm.; [Isoform 2]: Cytoplasm.
Target Protein Families
DIXDC1 family
Target Tissue Specificity
Ubiquitously expressed with higher expression in cardiac and skeletal muscles.
Target Synonyms
CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; Coiled coil DIX1 ; Coiled coil protein DIX1 ; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain containing protein 1; DIX domain-containing protein 1; DIXC1_HUMAN; DIXDC1; Dixin; KIAA1735
Target Background
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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