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The antibody against DMC1 was raised in rabbit using the Recombinant Human Meiotic recombination protein DMC1/LIM15 homolog protein (5-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DMC1 was raised in rabbit using the Recombinant Human Meiotic recombination protein DMC1/LIM15 homolog protein (5-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry analysis of human testis tissue using DMC1 Antibody at dilution of 1:1002
| Cat.No | ADC-08780A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DMC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Meiotic recombination protein DMC1/LIM15 homolog protein (5-153AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14565 |
Uniprot Id
Q14565
Target Species
Human
Target Name
DMC1
Target Full Name
Meiotic recombination protein DMC1/LIM15 homolog
Target Function
Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
RecA family, DMC1 subfamily
Target Synonyms
Disrupted meiotic cDNA 1 homolog ; Disrupted meiotic cDNA 1; yeast; homolog of; dJ199H16.1; DMC 1; DMC1; DMC1 dosage suppressor of mck1 homolog; DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast); DMC1 homologue ; DMC1_HUMAN; DMC1H; DNA meiotic recombinase 1; HsLim15; LIM15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473
Target Background
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.
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