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The antibody against DMKN was raised in rabbit using the Recombinant Human Dermokine protein (1-137AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against DMKN was raised in rabbit using the Recombinant Human Dermokine protein (1-137AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-25061A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DMKN |
| Target Synonyms | Dermokine antibody; DMKN antibody; DMKN_HUMAN antibody; Epidermis-specific secreted protein SK30/SK89 antibody; FLJ79374 antibody; UNQ729 antibody; UNQ729/PRO1411 antibody; ZD52F10 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dermokine protein (1-137AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6E0U4 |
Uniprot Id
Q6E0U4
Target Species
Human
Target Name
DMKN
Target Full Name
Dermokine
Target Function
May act as a soluble regulator of keratinocyte differentiation.
Target Subcellular Location
Secreted.
Target Protein Families
Dermokine family
Target Tissue Specificity
Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placenta. Isoform 1 is expr
Target Synonyms
Dermokine; DMKN; DMKN_HUMAN; Epidermis-specific secreted protein SK30/SK89; FLJ79374; UNQ729; UNQ729/PRO1411; ZD52F10
Target Background
This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
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