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The antibody against DOK3 was raised in rabbit using the Recombinant Human Docking protein 3 protein (1-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DOK3 was raised in rabbit using the Recombinant Human Docking protein 3 protein (1-146AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using DOK3 Antibody at dilution of 1:1002
| Cat.No | ADC-12806A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOK3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Docking protein 3 protein (1-146AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7L591 |
Uniprot Id
Q7L591
Target Species
Human
Target Name
DOK3
Target Full Name
Docking protein 3
Target Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
DOK family, Type A subfamily
Target Tissue Specificity
Expressed in spleen.
Target Synonyms
Docking protein 3; DOK 3; DOK Like Protein; Dok3; DOK3_HUMAN; DOKL Pending; Downstream of tyrosine kinase 3; p62 DOK Like Protein
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