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The antibody against DOK7 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human DOK7. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DOK7 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human DOK7. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
$297.00
Western blot analysis of extracts from mouse brain cells, using DOK7 antibody.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using DOK7 antibody.2
Immunofluorescence analysis of HepG2 cells, using DOK7 antibody.3
| Cat.No | ADC-41935A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOK7 |
| Target Synonyms | Docking protein 7 antibody; DOK 7 antibody; DOK7 antibody; DOK7_HUMAN antibody; Downstream of tyrosine kinase 7 antibody; Protein Dok-7 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human DOK7. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q18PE1 |
Uniprot Id
Q18PE1
Target Species
Human
Target Name
DOK7
Target Full Name
Protein Dok-7
Target Function
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Target Involvement
Myasthenic syndrome, congenital, 10 (CMS10)
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Cell junction, synapse.
Target Tissue Specificity
Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level).
Target Synonyms
Docking protein 7; DOK 7; DOK7; DOK7_HUMAN; Downstream of tyrosine kinase 7; Protein Dok-7
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