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The antibody against DUS2 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human DUS2L. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against DUS2 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human DUS2L. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Western blot analysis of extracts from RAW264.7 cells, using DUS2L antibody.
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L antibody.2
| Cat.No | ADC-41786A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DUS2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from C-terminal of Human DUS2L. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NX74 |
Uniprot Id
Q9NX74
Target Species
Human
Target Name
DUS2
Target Full Name
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Target Function
Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum.
Target Protein Families
Dus family, Dus2 subfamily
Target Tissue Specificity
Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level).
Target Synonyms
DUS2; DUS2LtRNA-dihydrouridine(20) synthase [NAD(P)+]-like; EC 1.3.1.91; Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2
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