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The antibody against EBF3 was raised in rabbit using the Recombinant Human Transcription factor COE3 protein (416-530AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against EBF3 was raised in rabbit using the Recombinant Human Transcription factor COE3 protein (416-530AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-06288A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EBF3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor COE3 protein (416-530AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H4W6 |
Uniprot Id
Q9H4W6
Target Species
Human
Target Name
EBF3
Target Full Name
Transcription factor COE3
Target Function
Transcriptional activator. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
Target Involvement
Hypotonia, ataxia, and delayed development syndrome (HADDS)
Target Subcellular Location
Nucleus.
Target Protein Families
COE family
Target Tissue Specificity
Expressed in brain.
Target Synonyms
COE 3; COE3; COE3_HUMAN; Early B cell factor 3; Early B-cell factor 3; EBF 3; EBF-3; EBF3; O/E 2; O/E-2; O/E2; OE 2; OE-2; OE2; Olf 1/EBF like 2; Olf-1/EBF-like 2; Transcription factor COE3
Target Background
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.
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